The Exposomics, Pollution, and Agriculture (EPA) group is dedicated to comprehending pollution sources and the pivotal processes influencing their impact on the environment. Our research spans from environmental chemistry to analytical chemistry, utilizing non-target screening and metabolomic methods to discern the effects of pollutants on both the environment and human health.
Main objectives:
We are a diverse and highly interdisciplinary team of scientists devoted to investigating the dynamics influencing the biological and chemical pollutants in environmental and agricultural ecosystems. Our research explores the processes that affect the toxicity and bioavailability of contaminants, and many aspects of health impact through the perspective of Exposomics.
Our main goal is to assess the presence, distribution, and fate of both natural and anthropogenic contaminants. This encompasses a wide range of substances, including priority and emerging contaminants, as well as metals and organometallic compounds. Our mission involves developing solutions to this global challenge by advancing methodologies, embracing nature-based approaches, and pioneering innovative sampling techniques for deployment across diverse environmental settings.
- Biogeochemistry of metals: investigates the fate, transport and impact of mercury and trace metals in aquatic ecosystems, with a particular focus on human exposure in regions affected by gold mining. This research entails the development of innovative samplers (passive samplers) for pollutant detection.
- Nature based solutions (NBS) and Agriculture: explores the use of NBS to reduce surface and groundwater pollution as well as the impact of chemical and biological pollutants on agricultural yield, crop metabolism, soil and human health.
- Human Biomonitoring and Exposomics: includes innovative analytical workflows aimed at exploring human exposure to chemicals and its link with the environment and health.
Exposoma químico y desarrollo del microbioma-resistoma desde el embarazo hasta la primera infancia
PID2025-175175OA-I00
By characterizing the chemical exposome in pregnancy and early-life and assessing its effects on maternal-infant microbiome and resistome development, the project addresses key challenges identified in these priority areas, including the need to monitor emerging contaminants, understand their biological effects and support policies aimed at reducing environmental health risks. Specifically, CHEM-BIOME uses advanced high resolution mass spectrometry (HRMS) and metagenomics approaches to quantify a wide range of organic pollutants, many of them linked to consumer products and food packaging, and through metagenomics it evaluates how these exposures affect the maternal-infant development of the microbiome and resistome.
The project follows a holistic and interdisciplinary approach to assess the impact of the chemical exposome on maternal-infant microbiome and resistome development from pregnancy to early-life, combining expertise in exposomics, microbiology, epidemiology and clinical translation.
Proyecto PID2025-175175OA-I00 financiado por MICIU/AEI /10.13039/501100011033 y por FEDER, UE
Start Date: 01/10/2026 – End Date: 30/09/2029
Desentrañando el impacto metabólico de la exposición a contaminantes: cómo las mezclas moldean la enfermedad hepática grasa asociada a disfunción metabólica durante la vida
PID2025-175615OA-I00
Proyecto PID2025-175615OA-I00 financiado por MICIU/AEI /10.13039/501100011033 y por FEDER, UE
Start Date: 01/11/2026 – End Date: 31/10/2029
Soluciones basadas en la naturaleza mejoradas con biochar para cumplir la Directiva >Europea de Aguas Residuales Urbanas (WET-CHAR)
202680E015
PROYECTOS INTRAMURALES CSIC(2025)
Start Date: 01/01/2026 – End Date: 31/12/2029
Evaluación del Exposoma Químico en el Embarazo y su Papel en el Desarrollo de la Diabetes Mellitus Gestacional
CNS2024-154628
PREGO es un proyecto de investigación innovador que tiene como objetivo evaluar el papel potencial del exposoma químico en el desarrollo de la diabetes mellitus gestacional (DMG), una condición caracterizada por niveles altos de glucosa en sangre que se desarrolla por primera vez durante el embarazo. La DMG puede provocar complicaciones tanto a corto como a largo plazo para la madre y el hijo. En España, se estima que más de 40.000 mujeres son diagnosticadas con DMG cada año. A pesar de los factores conocidos como la predisposición genética y el estilo de vida, la influencia de las exposiciones a químicos ambientales sigue siendo poco explorada.
PREGO se desarrollará en el marco de la cohorte INSULIN, establecida en 2021 en el Hospital Universitario Joan XXIII (HJXXIII) en Tarragona, España, que comprende más de 500 embarazadas. Para este proyecto, analizaremos de manera integral 300 muestras emparejadas de orina y sangre materna, juntamente con placenta, para caracterizar el exposoma químico y su impacto en el desarrollo de la DMG. Además, PREGO examina factores clínicos, sociodemográficos, dietéticos y de estilo de vida para revelar asociaciones entre las exposiciones ambientales y la incidencia de DMG. Esto incluye explorar cómo estos factores pueden modificar los efectos de los químicos en los resultados de salud. Finalmente, los hallazgos de PREGO facilitarán el desarrollo e implementación de un programa piloto de prevención en el HJXXIII destinado a reducir la exposición a químicos dañinos durante el embarazo.
PREGO proporcionará valiosos conocimientos para los profesionales de la salud y los responsables de políticas. Al identificar y mitigar el impacto de las exposiciones ambientales nocivas durante el embarazo, el equipo de investigación se dedicará a guiar la implementación de medidas proactivas para reducir la carga química, contribuyendo a mejorar la salud materna y fetal.
Ayuda CNS2024-154628 financiada por MICIU/AEI /10.13039/501100011033
Start Date: 01/04/2025 – End Date: 31/03/2027
Soil remediation of per- and polyfluoroalkyl substances (PFAS) to layered double hydroxides (LDHs) ¿ Development, regeneration and mechanisms for injectable soil encapsulating sorbent (LDH-PFAS-SORP)
101204389
This project has received funding from the European Union’s Horizon Europe research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101204389
Start Date: 01/09/2026 – End Date: 31/08/2028
Análisis de contaminantes emergentes en muestras de suero procedentes de la cohorte Aragon Worker’s Health Study, financiado por el Instituto de Salud Carlos III mediante el proyecto PI24/00479 y cofinanciado por la Unión Europea
CONTRATO
Start Date: 16/01/2026 – End Date: 15/01/2028
Evaluación de los efectos toxicológicos del consumo de cultivos regados con aguas regeneradas por presencia de contaminantes emergentes y persistentes
Programa CSIC de Movilidad Internacional para Personal Predoctoral
Start Date: 01/01/2024 – End Date: 31/12/2026
Agua Reutilizada en Barcelona: Evaluación de Riesgos Microbiológicos y Resistencia Antimicrobiana en Aguas Grises Tratadas (GreyWaterBCN).
2025_OVT_280016
Projecte finançat per l'Ajuntament de Barcelona i la Fundació "La Caixa" de la 5a edició de la convocatòria de subvencions de Recerca i Innovació.
L'objectiu d'aquest projecte és avaluar de manera integral els riscos microbiològics associats a la reutilització d’aigües grises en entorns urbans, amb especial atenció a la presència de patògens i a la propagació de la resistència als antibiòtics (RAM). L’estudi analitzarà la qualitat microbiològica d’aigües grises tractades i els aerosols generats durant el seu ús en aplicacions com el reg d’espais verds, comparant diferents sistemes de tractament i aplicant tècniques metagenòmiques d’última generació. Aquest coneixement serà clau per establir recomanacions que garanteixin un ús segur i sostenible d’aquest recurs.
Start Date: 31/12/2025 – End Date: 31/12/2027
BioRisk
Holistic assessment of the impact-interaction of chemical and microbiological micropollutats in the biosolid-soil-plant system. Risks and agricultural recommendations.
The BIORISK project focuses on the holistic evaluation of the impact of chemical and microbial micropollutants in the biosolid-soil-plant system. Biosolids, derived from sewage sludge, are widely used in agriculture as organic fertilizers due to their high nutrient content and role in promoting circular economy principles. However, their application may introduce emerging contaminants such as pharmaceuticals, heavy metals, and antibiotic-resistant bacteria into the soil, crops, and ultimately, the food chain. BIORISK aims to assess the risks associated with biosolid use in farming and explore innovative strategies to mitigate pollutant uptake, ensuring safe and sustainable agricultural practices.
The use of biosolids in agriculture presents both opportunities and risks. On one hand, they provide essential nutrients to crops, improve soil health, and reduce the need for synthetic fertilizers. On the other hand, biosolids may contain a mix of chemical pollutants (e.g., pharmaceuticals, pesticides, plasticizers, and heavy metals) and microbial contaminants (e.g., antibiotic-resistant bacteria and genes), which could pose risks to human health and the environment.
Currently, European regulations on biosolid use mainly focus on heavy metal content, leaving emerging pollutants unregulated. This knowledge gap makes it difficult to determine safe application levels and long-term impacts on soil, crops, and consumers. Without clear guidelines, farmers and policymakers lack the necessary tools to ensure food safety and environmental protection. BIORISK addresses these challenges by conducting comprehensive research to understand pollutant dynamics and develop mitigation strategies.
Funding: cofunded by the EU
Start Date: 01/03/2024 – End Date: 30/11/2026
https://biorisk.csic.es/
ARISE
Atmospheric antimicrobial resistance spread
ARISE is an interdisciplinary and innovative project in the field of fine particulate matter (PM2.5) aerosol pollution. ARISE aims to identify chemical markers (i.e., specific group of organic molecules or chemical families) in the PM2.5 possibly associated with antibiotic resistance bacteria (ARB), antibiotic resistance genes (ARGs) and mobile genetic elements (MGE) present in the air. Beside the evidences that airborne fine particulate matters can be a successful conduit for long-range dispersal of resistance, to the best of our knowledge there are no studies that have evaluated the link between the chemical and microbiological components of PM2.5 and the impact they could generate on the AMR spread in the air. ARISE represents the first attempt to identify the chemical markers of airborne PM2.5 conveying atmospheric AMR spread, in line with the ‘One Health’ approach to address the collective need of reducing the environmental AMR burden.
Entidad financiadora: Fundación "La Caixa". Becas de Posdoctorado Junior Leader – Incoming, convocatoria 2023
Start Date: 01/06/2024 – End Date: 31/05/2027
Staff
Permanent Researchers
PhD Students
Postdoc Researchers
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